Engineering Biology: Cells and Tissues|
This course explores the intersection of biology, medicine, and engineering, where scientists are developing novel platforms to promote understanding, diagnosis, and treatment of human diseases. We cover modern techniques for manipulating biological systems, spanning single molecules to ensembles of cells. We will examine the trajectory of the field from studying cells in a plastic dish to the advent of organ-on-a-chip and organoid models and discuss how this transition from 2D to 3D biology has propelled increased understanding of both normal physiological homeostasis and also the pathophysiology of disease. Topics will include controlling behavior of cells through cell-matrix interactions, learning through building via synthetic biology, and advances in regenerative medicine. These topics will be explored through the thematic lenses of transport processes (supply of nutrients and removal of waste) and mechanoreciprocity (the sensing of and response to the physical properties of the cellular microenvironment). Lectures will review fundamental concepts in cell biology and physiology before delving into topical examples from current literature. Lectures and assessments will include opportunities to develop skill in thinking analytically and critically about using engineering tools to study fundamental questions in human disease, formulating original ideas and experiments, and communicating science through written and oral formats.
||Gen Ed Area Dept:
|Course Format: Discussion||Grading Mode: Graded|
||Prerequisites: MB&B181 AND MB&B182
||Fulfills a Major Requirement for: (BIOL)(IDEA-MN)(INFO-MN)
||Past Enrollment Probability: 90% or above
|Major Readings: Wesleyan RJ Julia Bookstore
Readings will be available through the course Moodle
|Examinations and Assignments: |
Course participation and homework, quizzes, design projects.
|Additional Requirements and/or Comments: |
Students should have completed MB&B 181/191.
|Instructor(s): Mitchel,Jennifer Times: ..T.R.. 02:50PM-04:10PM; Location: SCIE137; |
|Total Enrollment Limit: 25||SR major: 8||JR major: 7|| || |
|Seats Available: 3||GRAD: X||SR non-major: 6||JR non-major: 4||SO: X||FR: X|
|Drop/Add Enrollment Requests|
|Total Submitted Requests: 1||1st Ranked: 0||2nd Ranked: 0||3rd Ranked: 0||4th Ranked: 0||Unranked: 1|