Lab in Cell and Molecular Neurobiology
BIOL 250
Fall 2006 not offered
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Crosslisting:
NS&B 250 |
In recent years, an explosion of molecular and cellular techniques has revolutionized the way neuroscientists visualize the structure and function of the central nervous system. The goal of this lab course is to introduce students to hot topics in developmental neuroscience and to provide training in some experimental approaches. The topical focus of the course in 2007 will be to examine how epilepsy causes a reorganization of the adult hippocampus. Students will study neural stem cells, neurodegeneration, and hippocampal function by mastering techniques for: growing cell cultures, sectioning brain tissue, and by performing immunocytochemical staining to detect neurogenesis and cell death in the adult hippocampus. In addition, the class will gain experience with behavioral analyses of an animal model of epilepsy. Some class time will also be devoted to design of experiments and formulating testable hypotheses. Upon mastery of basic techniques, students will work in small groups on individual projects and present their research in a poster session. Grades are based on laboratory notebooks, independent project work, poster presentations, and a short written research proposal. |
Essential Capabilities:
Quantitative Reasoning |
Credit: 1 |
Gen Ed Area Dept:
NSM BIOL |
Course Format: Laboratory | Grading Mode: Graded |
Level: UGRD |
Prerequisites: None |
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Fulfills a Major Requirement for: (BIOL)(NS&B) |
Major Readings:
THE RAT NERVOUS SYSTEM: AN INTRODUCTION TO PREPARATORY TECHNIQUES by J. P. Cassella (Author), J. Hay (Author), S. J. Lawson (Author), Publisher: John Wiley & Son Ltd; 1st edition (January 15, 1997) ISBN: 0471969672
A BEGINNER'S GUIDE TO SCIENTIFIC METHOD by Stephen S. Carey, Edition: Paperback, Publisher: Wadsworth Publishing; 2 edition (June 27, 1997) ISBN: 0534528430
FLUORESCENCE MICROSCOPY (MICROSCOPY HANDBOOKS, 40) by H. J. Tanke, Brian Herman, Edition: Paperback, Publisher: Springer Verlag; 2nd edition (May 1998) ISBN: 0387915516
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Examinations and Assignments: Laboratory notebook, lab reports, 2 short scientific essays, lab method practical exam, poster presentation of research projects. |
Additional Requirements and/or Comments: The time in the laboratory and outside readings are estimated to take approximately 8-10 hours/week. Because of the project-oriented nature of the course, students will be expected to return to the lab at various times during the week to complete experiments. |
Drop/Add Enrollment Requests | | | | | |
Total Submitted Requests: 0 | 1st Ranked: 0 | 2nd Ranked: 0 | 3rd Ranked: 0 | 4th Ranked: 0 | Unranked: 0 |
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