Practical and Theoretical NMR
CHEM 382
Spring 2022
| Section:
01
|
| Crosslisting:
MB&B 382 |
Nuclear magnetic resonance (NMR) is an extremely powerful and flexible technique that can be used to analyze molecules sized from just a few atoms up to tens of thousands of atoms. This course will provide an introduction to how NMR spectroscopy works and background on the important theoretical aspects relevant for the most common NMR experiments. Time will be spent gaining practical experience in conducting NMR experiments both during and outside class. The ultimate goal of both the theoretical and hands on sections of this course is to enable you to correctly select and perform NMR experiments necessary to characterize molecules. In addition to learning how NMR hardware is used to produce spectra, we also cover important tasks like sample preparation and the finer points of data processing that will help you get better data. Beyond simple one-dimensional experiments, we will discuss a number of different multidimensional NMR experiments for determining the structures of small organic molecules, including COSY, HSQC, HMBC, and NOE. Furthermore, you will learn how protein structures are solved using 2D and 3D experiments, and how the motion of those proteins can be measured at the atomic level. |
|
| Credit: 1 |
Gen Ed Area Dept:
NSM CHEM |
| Course Format: Lecture / Discussion | Grading Mode: Graded |
| Level: UGRD |
Prerequisites: None |
|
Fulfills a Requirement for: (CHEM-MN)(CHEM-Track A)(CHEM-Track B)(MB&B)(MOBI-MN) |
|
Past Enrollment Probability: 90% or above |
| SECTION 01 |
Major Readings: Wesleyan RJ Julia Bookstore
Timothy D.W. Claridge: High-Resolution NMR Techniques in Organic Chemistry, 3rd Edition ISBN: 978-0-080-99986-9 Optional Reading: James Keeler: Understanding NMR Spectroscopy, 2nd Edition ISBN: 978-0-470-74608-0
|
Examinations and Assignments:
|
Additional Requirements and/or Comments:
|
| Instructor(s): Smith,Colin A. Times: .M.W.F. 09:50AM-10:40AM; Location: HALL56; |
| Total Enrollment Limit: 19 | | SR major: 4 | JR major: 3 | | |
| Seats Available: 9 | GRAD: X | SR non-major: 3 | JR non-major: 3 | SO: 3 | FR: 3 |
| Drop/Add Enrollment Requests | | | | | |
| Total Submitted Requests: 0 | 1st Ranked: 0 | 2nd Ranked: 0 | 3rd Ranked: 0 | 4th Ranked: 0 | Unranked: 0 |
|
|