Principles of Biology I: Cell Biology and Molecular Basis of Heredity
MB&B 181
Fall 2011
| Section:
01
02
03
04
05
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| Crosslisting:
BIOL 181 |
| Certificates: Informatics and Modeling |
This course presents an entrance-level exploration of the contemporary view of the cell and an introduction to the molecules and mechanisms of genetics. The course will begin with a general introduction to the principles of biology and the concept of the gene. The first half of the course will focus on the DNA molecule as the genetic material, and the "central dogma" of molecular biology describing the process of information transfer from the genetic code to protein synthesis and function. Topics include DNA replication, DNA mutation and repair, chromosome dynamics, RNA transcription and transcriptional regulation, protein translation, protein structure, posttranslational regulation of protein function, signal transduction and the molecular basis of cellular behavior. The second half of the course will focus on cell theory and the underlying molecular mechanisms of cellular activities. Topics will include membrane dynamics, energetics, the cytoskeleton, cell motility, the cell cycle, mitosis, meiosis, and nuclear and chromosome structure. To demonstrate the scientific process, lectures will stress the experimental basis for the conclusions presented. |
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Essential Capabilities:
Interpretation, Quantitative Reasoning
Students will interpret various forms of experimental data in order to infer biological meaning.
Students will analyze experimental data that is quantitative in nature, as well as apply statistical approaches, in order to understand important scientific advances in biology.
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| Credit: 1 |
Gen Ed Area Dept:
NSM MB&B |
| Course Format: Lecture | Grading Mode: Graded |
| Level: UGRD |
Prerequisites: None |
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Fulfills a Requirement for: (BIOL)(CHEM-Track B)(E&ES)(INFO-MN)(MB&B)(NS&B)(STS) |
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Past Enrollment Probability: Not Available |
| SECTION 01 |
Major Readings: Wesleyan RJ Julia Bookstore
Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander Johnson, Julia Lewis, Martin Raff, Keith Roberts and Peter Walter, ESSENTIAL CELL BIOLOGY, 3rd ed. |
Additional Requirements and/or Comments:
Students with a particularly strong background in biology may be interested in enrolling in the honors level component of this course, BIOL/MB&B 195. Students are encouraged to participate in a "4th hour" session each week (scheduling TBD) to reinforce the major concepts of the lecture classes. In addition, the course will have multiple scheduled office hours by faculty and teaching assistants. MB&B 191 is to be taken concurrently and registered for separately, except by permission of the instructor. A strong background in chemistry is desirable and it is recommended that students be enrolled in the Introductory Chemistry series concurrently (or have taken it previously). |
| Instructor(s): Holmes,Scott G. Lane,Robert P. McAlear,Michael A. Hingorani,Manju Times: .M.W.F. 10:00AM-10:50AM; Location: SCIE150; |
| Total Enrollment Limit: UNL | | SR major: UNL | JR major: UNL | | |
| Seats Available: UNL | GRAD: X | SR non-major: UNL | JR non-major: UNL | SO: UNL | FR: UNL |
| Drop/Add Enrollment Requests | | | | | |
| Total Submitted Requests: 0 | 1st Ranked: 0 | 2nd Ranked: 0 | 3rd Ranked: 0 | 4th Ranked: 0 | Unranked: 0 |
| SECTION 02 |
Major Readings: Wesleyan RJ Julia Bookstore
Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander Johnson, Julia Lewis, Martin Raff, Keith Roberts and Peter Walter, ESSENTIAL CELL BIOLOGY, 3rd ed. |
Examinations and Assignments:
Problem sets and three exams. |
Additional Requirements and/or Comments:
This small enrollment section is a good choice for students preferring greater emphasis on continuous assessment and problem based learning. Given the small enrollment, this section is also a good choice for students with less extensive previous backgrounds in biology. The information role of DNA and proteins in molecular cellular biology will be a central theme throughout the course. Section 2 will address similar topics to Section 1. Students should enroll separately in MB&B/BIOL191. |
| Instructor(s): Weir,Michael P. Times: .M.W.F. 10:00AM-10:50AM; Location: HALL84; |
| Total Enrollment Limit: 16 | | SR major: 0 | JR major: 0 | | |
| Seats Available: -4 | GRAD: X | SR non-major: 0 | JR non-major: 0 | SO: 0 | FR: 16 |
| Drop/Add Enrollment Requests | | | | | |
| Total Submitted Requests: 1 | 1st Ranked: 1 | 2nd Ranked: 0 | 3rd Ranked: 0 | 4th Ranked: 0 | Unranked: 0 |
| SECTION 03 |
Major Readings: Wesleyan RJ Julia Bookstore
Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander Johnson, Julia Lewis, Martin Raff, Keith Roberts and Peter Walter, ESSENTIAL CELL BIOLOGY, 3rd ed. |
Examinations and Assignments:
Problem sets and three exams. |
Additional Requirements and/or Comments:
This small enrollment section is a good choice for students preferring greater emphasis on continuous assessment and problem based learning. Given the small enrollment, this section is also a good choice for students with less extensive previous backgrounds in biology. The information role of DNA and proteins in molecular cellular biology will be a central theme throughout the course. Section 3 will address similar topics to Section 1. Students should enroll separately in MB&B/BIOL191. |
| Instructor(s): Weir,Michael P. Times: .M.W... 10:00AM-10:50AM; .....F. 01:10PM-02:00PM; Location: HALL84; HALL84; |
| Total Enrollment Limit: 16 | | SR major: 0 | JR major: 0 | | |
| Seats Available: -4 | GRAD: X | SR non-major: 0 | JR non-major: 0 | SO: 0 | FR: 16 |
| Drop/Add Enrollment Requests | | | | | |
| Total Submitted Requests: 1 | 1st Ranked: 0 | 2nd Ranked: 1 | 3rd Ranked: 0 | 4th Ranked: 0 | Unranked: 0 |
| SECTION 04 |
Major Readings: Wesleyan RJ Julia Bookstore
Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander Johnson, Julia Lewis, Martin Raff, Keith Roberts and Peter Walter, ESSENTIAL CELL BIOLOGY, 3rd ed. |
Examinations and Assignments:
Problem sets and three exams. |
Additional Requirements and/or Comments:
This small enrollment section is a good choice for students preferring greater emphasis on continuous assessment and problem based learning. Given the small enrollment, this section is also a good choice for students with less extensive previous backgrounds in biology. The information role of DNA and proteins in molecular cellular biology will be a central theme throughout the course. Section 4 will address similar topics to Section 1. Students should enroll separately in MB&B/BIOL191. |
| Instructor(s): Murolo,Michelle Aaron Times: .M.W.F. 11:00AM-11:50AM; Location: HALL84; |
| Total Enrollment Limit: 16 | | SR major: 0 | JR major: 0 | | |
| Seats Available: -2 | GRAD: X | SR non-major: 0 | JR non-major: 0 | SO: 0 | FR: 16 |
| Drop/Add Enrollment Requests | | | | | |
| Total Submitted Requests: 1 | 1st Ranked: 0 | 2nd Ranked: 1 | 3rd Ranked: 0 | 4th Ranked: 0 | Unranked: 0 |
| SECTION 05 |
Major Readings: Wesleyan RJ Julia Bookstore
Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander Johnson, Julia Lewis, Martin Raff, Keith Roberts and Peter Walter, ESSENTIAL CELL BIOLOGY, 3rd ed. |
Examinations and Assignments:
Problem sets and three exams. |
Additional Requirements and/or Comments:
This small enrollment section is a good choice for students preferring greater emphasis on continuous assessment and problem based learning. Given the small enrollment, this section is also a good choice for students with less extensive previous backgrounds in biology. The information role of DNA and proteins in molecular cellular biology will be a central theme throughout the course. Section 5 will address similar topics to Section 1. Students should enroll separately in MB&B/BIOL191. |
| Instructor(s): Murolo,Michelle Aaron Times: .M.W... 11:00AM-11:50AM; .....F. 01:10PM-02:00PM; Location: HALL84; SCIE139; |
| Total Enrollment Limit: 16 | | SR major: 0 | JR major: 0 | | |
| Seats Available: -1 | GRAD: X | SR non-major: 0 | JR non-major: 0 | SO: 0 | FR: 16 |
| Drop/Add Enrollment Requests | | | | | |
| Total Submitted Requests: 4 | 1st Ranked: 0 | 2nd Ranked: 1 | 3rd Ranked: 1 | 4th Ranked: 1 | Unranked: 1 |
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