MB&B 506
Spring 2025
| Section:
01
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| Crosslisting:
MB&B 306 |
Basic genetics states that individuals with different DNA sequences express different traits. However, a large number of permanent and heritable changes to cells and organisms occur in the absence of changes to DNA sequence. Such epigenetic mechanisms explain a variety of disparate observations, including the ability of a zygote to develop into dozens of distinct cell types in multicellular organisms using one common DNA blueprint, the observation that grandchildren of individuals subject to famine have higher rates of metabolic defects, and the ability of neurons to mediate formation of long-term memories. In this course we will use a variety of examples from cell biology and genetics to examine the template-dependent processes governing the perpetuation of discrete phenotypes. Topics will include the molecular biology of prions (infectious proteins) and environment-induced alterations in gene expression that may be transmitted to offspring. |
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| Credit: 1 |
Gen Ed Area Dept:
NSM MB&B |
| Course Format: Lecture | Grading Mode: Graded |
| Level: GRAD |
Prerequisites: MB&B181 |
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Fulfills a Requirement for: (BIOL)(MB&B) |
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Past Enrollment Probability: 75% - 89% |
| SECTION 01 |
Major Readings: Wesleyan RJ Julia Bookstore
The course is taught using research and review articles from the primary literature.
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Examinations and Assignments:
Course evaluations will include midterms, homeworks, and a final exam. Discussion in class is expected. |
Additional Requirements and/or Comments:
MB&B 208 is recommended but no required. |
| Instructor(s): Holmes,Scott Times: ..T.R.. 08:50AM-10:10AM; Location: SHAN201; |
| Total Enrollment Limit: 25 | | SR major: 8 | JR major: 8 | | |
| Seats Available: 13 | GRAD: 3 | SR non-major: 0 | JR non-major: 0 | SO: 6 | FR: 0 |
| Drop/Add Enrollment Requests | | | | | |
| Total Submitted Requests: 0 | 1st Ranked: 0 | 2nd Ranked: 0 | 3rd Ranked: 0 | 4th Ranked: 0 | Unranked: 0 |
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