Cellular Mechanisms of Gene Regulation and Gene Editing Tools
MB&B 233
Spring 2023
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01
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This course will explain the mechanisms of gene expression in eukaryotes. Then we will define the main and current techniques used for gene editing (CRISPR/Cas9, TALEN, site director mutagenesis, CRE/Lox recombination). Discussions will include how these technologies can be used to optimize organisms for health, food, and energy applications. Ethical use and current regulations of gene editing tools will also be considered. |
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| Credit: 1 |
Gen Ed Area Dept:
NSM MB&B |
| Course Format: Lecture / Discussion | Grading Mode: Graded |
| Level: UGRD |
Prerequisites: MB&B181 |
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Fulfills a Requirement for: (MB&B) |
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Past Enrollment Probability: 75% - 89% |
| SECTION 01 |
Major Readings: Wesleyan RJ Julia Bookstore
Hartwell et al., Genetics: from genes to genomes, 6th Ed.
Alberts, B. et al., MOLECULAR BIOLOGY OF THE CELL, 6th ed.
Appasani et al. Genome Editing and Engineering: From TALENs, ZFNs and CRISPRs to Molecular Surgery 1st Ed.
Selected readings from primary literature and case studies
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Examinations and Assignments:
Students will give presentations on primary literature related to a case-study homework. Weekly online quizzes and final exam. |
Additional Requirements and/or Comments:
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| Instructor(s): Padilla-Benavides,Teresita Times: .M.W... 11:10AM-12:30PM; Location: SCIE74; |
| Total Enrollment Limit: 19 | | SR major: 6 | JR major: 6 | | |
| Seats Available: 3 | GRAD: X | SR non-major: 1 | JR non-major: 2 | SO: 4 | FR: 0 |
| Drop/Add Enrollment Requests | | | | | |
| Total Submitted Requests: 0 | 1st Ranked: 0 | 2nd Ranked: 0 | 3rd Ranked: 0 | 4th Ranked: 0 | Unranked: 0 |
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