Physical Chemistry for the Life Sciences|
CHEM 381, MB&B 581|
|Certificates: Environmental Studies, Molecular Biophysics, Molecular Biophysics|
The course is concerned with the basic physicochemical principles and model systems essential to understanding, explaining and predicting the behavior of biological systems in terms of molecular forces. PCLS integrates fundamental concepts in thermodynamics, kinetics, and molecular spectroscopy with the structures, functions and molecular mechanisms of biological processes. The objective of the course is to a) familiarize life science students at the advanced undergraduate and beginning graduate level with basic physico-chemical laws, theories and concepts important to the life sciences, b) provide a working knowledge of mathematical methods useful in the life science research, c) develop a critical perspective on explanation of biological processes and understanding biological systems, and d) survey the main applications of physical chemistry in the life sciences with an emphasis on spectroscopy and microscopy. Theory, methodology, and biophysical concepts are distributed throughout the course, and presented in the context of case studies include respiration, light harvesting and photosynthesis, ATP hydrolysis, NAD/NADH redox, energy transfer, FRET spectroscopy, with an emphasis on single molecule as well as ensemble experiments and their interpretation.
||Gen Ed Area Dept:
|Course Format: Lecture||Grading Mode: Graded|
||Prerequisites: (CHEM141 AND CHEM142 AND MATH117 AND CHEM251) OR (CHEM143 AND CHEM144 AND MATH121 AND CHEM251)
||Fulfills a Major Requirement for: (CES)(CHEM-MN)(CHEM)(CIS)(CMB)(ENVS)(IDEA-MN)(MB&B)
||Past Enrollment Probability: Not Available
|Major Readings: Wesleyan RJ Julia Bookstore
I.Tinoco Jr, K.Sauer and J.C.Wang, PHYSICAL CHEMISTRY - PRINCIPLES AND APPLICATIONS IN THE BIOLOGICAL SCIENCES, 4th ed., Prentice Hall, New York 2002.
|Examination and Assignments: |
Weekly problem sets, three exams and a final poster presentation.
|Additional Requirements and/or Comments: |
Organic chemistry, at least taken concurrently, is necessary to understand some of the applications.
|Instructor(s): Beveridge,David L. Times: ..T.R.. 02:40PM-04:00PM; ...W... 07:00PM-09:00PM; Location: TBA|
|Total Enrollment Limit: UNL||SR major: UNL||JR major: UNL|| || |
|Seats Available: UNL||GRAD: UNL||SR non-major: UNL||JR non-major: UNL||SO: UNL||FR: UNL|
|Drop/Add Enrollment Requests|
|Total Submitted Requests: 0||1st Ranked: 0||2nd Ranked: 0||3rd Ranked: 0||4th Ranked: 0||Unranked: 0|