Physical Chemistry for the Life Sciences|
CHEM 381, MB&B 581|
|Certificates: Environmental Studies, Molecular Biophysics, Molecular Biophysics|
|Course Cluster: Health Studies|
The course is concerned with the basic physicochemical principles and model systems essential to understanding, explaining, and predicting the behavior of biological systems in terms of molecular forces. PCLS integrates fundamental concepts in thermodynamics, kinetics, and molecular spectroscopy with the structures, functions, and molecular mechanisms of biological processes. The objectives of the course are to (a) familiarize life science students at the advanced undergraduate and beginning graduate level with basic physicochemical laws, theories, and concepts important to the life sciences; (b) provide a working knowledge of mathematical methods useful in the life science research; (c) develop a critical perspective on explanation of biological processes and understanding biological systems; and (d) survey the main applications of physical chemistry in the life sciences with an emphasis on spectroscopy and microscopy. Theory, methodology, and biophysical concepts are distributed throughout the course and are presented in the context of case studies including respiration, light harvesting and photosynthesis, ATP hydrolysis, NAD/NADH redox, energy transfer, FRET spectroscopy, with an emphasis on single molecule as well as ensemble experiments and their interpretation.
||Gen Ed Area Dept:
|Course Format: Lecture||Grading Mode: Graded|
||Prerequisites: (CHEM141 AND CHEM142 AND MATH117 AND CHEM251) OR (CHEM143 AND CHEM144 AND MATH121 AND CHEM251)
||Fulfills a Major Requirement for: (CES)(CHEM)(CIS)(CMB)(ENVS)(IDEA-MN)(MB&B)
||Past Enrollment Probability: 90% or above
|Major Readings: Wesleyan RJ Julia Bookstore
John Kuriyan, Boyana Konforti and David Wemmer
THE MOLECULES OF LIFE: PHYSICAL AND CHEMICAL PRINCIPLES
Publisher: Garland Science
|Examination and Assignments: |
Weekly problem sets, three exams and a final poster presentation.
|Additional Requirements and/or Comments: |
Organic chemistry, at least taken concurrently, is necessary to understand some of the applications.
|Instructor(s): Mukerji,Ishita Times: ..T.R.. 10:20AM-11:40AM; Location: TBA|
|Total Enrollment Limit: 25||SR major: 8||JR major: 9|| || |
|Seats Available: 3||GRAD: 1||SR non-major: 2||JR non-major: 2||SO: 3||FR: 0|