Enzymology of DNA Damage and Repair|
Spring 2019 not offered
Students in this course will learn about the sources and consequences of DNA damage and the biochemical mechanisms responsible for DNA repair. Course content will include lectures, student presentations, and discussion of current literature on DNA damage, repair and mutagenesis, with strong emphasis on protein structure-function and enzyme kinetics, as well as diseases associated with defective DNA repair.
||Gen Ed Area Dept:
|Course Format: Lecture / Discussion||Grading Mode: Graded|
||Fulfills a Major Requirement for: (MB&B)(MOBI-MN)
Errol C. Friedberg, Graham C. Walker, Wolfram Siede, Richard D. Wood, Roger A. Schultz, Tom Ellenberger, DNA REPAIR AND MUTAGENESIS, 2nd edition (ASM Press, 2005)
Research articles from journals such as Science, Nature, PNAS USA, Cell, EMBO J, Molecular Cell, etc.
|Examinations and Assignments: |
In-class participation, one mid term exam and a take-home final exam, as well as a few short problem-solving/essay assignments.
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