Molecular, Proteomic, and Cell Biological Analysis of Telomere Composition and Function|
Fall 2012 not offered
This course will focus on a critical feature of the eukaryotic cell known as the telomere, or linear chromosome end. We will discuss the diverse set of critical molecular mechanisms affected by and involving telomeres including chromosome segregation, cellular aging, meiotic gamete production, and cancer progression. We will also focus on the physical architecture of the telomere, how this architecture dynamically alters in different biological contexts, and the types of molecules known to associate with telomeres in multiple model organisms including yeast and human cells. An emphasis will be placed on experimental strategies used for identifying new components of the telomere complex and for understanding telomere function during normal and diseased cellular states.
||Gen Ed Area Dept:
|Course Format: Lecture||Grading Mode: Graded|
||Fulfills a Major Requirement for: (MB&B)
Alberts et al., MOLECULAR BIOLOGY OF THE CELL, 4th edition
and current literature
|Examinations and Assignments: |
|Additional Requirements and/or Comments: |
Research approaches in the instructor's laboratory will be included.
This is a second quarter course. The first class will be October 20.
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