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Mechanisms of Chromosome Segregation
MB&B 314
Fall 2009 not offered
Crosslisting: MB&B 514

This course will focus on various aspects of eukaryotic chromosome segregation and genome stability, with particular focus on the centrosome/spindle pole body, the mitotic spindle apparatus, and the telomeric ends of linear chromosomes. We will discuss the physical architecture of these structures, the core molecular components comprising them, and the remarkable degree of functional conservation between these structures from organisms as diverse as yeast and humans. We will explore how the physical structure of these cellular structures undergoes extensive, dynamic alteration to facilitate different functions in various biological contexts. An emphasis will be placed on current experimental strategies used for identification of critical proteins associated with these structures and the powerful set of molecular and cellular methods available for characterizing their functions in both normal and diseased cells.

Essential Capabilities: None
Credit: 1 Gen Ed Area Dept: None
Course Format: DiscussionGrading Mode: Graded
Level: UGRD Prerequisites: None
Fulfills a Major Requirement for: None

Last Updated on JUL-21-2024
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