Spring 2010 not offered
Ribosomes are large, complex, rRNA- and protein-containing cellular machines that translate the information of nucleic acids (mRNAs) into the amino acid language of polypeptides. The biosynthesis of ribosomes constitutes a major fraction of the total cellular economy, and this process is regulated in response to many different cellular stimuli. In this course we will consider how the hundreds of required gene products combine to effect ribosome biosynthesis, as well as how the structure of the ribosome contributes to its function. We will also consider how perturbations in ribosome function relate to aspects of molecular medicine including antibiotics and cellular toxins.
||Gen Ed Area Dept:
|Course Format: Lecture||Grading Mode: Graded|
||Fulfills a Major Requirement for: None
|Examinations and Assignments: |
The course will include lectures and considerations of primary research articles. Students will be expected to submit a paper and present a ribosome-related discussion to the class. In addition, there will be two class tests, but no final exam.
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